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The story follows (Demi Moore), a fading Hollywood star and fitness show host who is unceremoniously fired by her obnoxious producer, Harvey (Dennis Quaid), on her 50th birthday. Desperate to regain her relevance, she turns to a mysterious black-market drug known as "The Substance". Review: The Substance • Flixist The Substance -2024- English 480p Web-DL.mkv Filmyfly.Com